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Dosing by Slow-Release Pill

The mode of drug administration influences the rate at which effective plasma concentrations are achieved. A loading dose also allows earlier achievement of effective concentrations.

Observe how the drug concentration-time profiles for IV versus oral dosing, with and without loading doses.

Then see how slow release pills allow longer dose intervals. A loading dose can also be used with slow release pills.

Pill Animation Pill Animation Arrow Animation
Pill Animation Pill Animation Arrow Animation

Cp

Time (h)

minimum toxic concentration

minimum effective concentration

CLEARANCE

Dosing by slow-release-pill: