t1/2, Vd & Cl
The half-life (t1/2) is a dependent variable, dependent on the 2 independent variables Cl and Vd.
t1/2 = 0.693 x VD/CL
Adjust the Cl to see what happens to the t1/2 and the Cp-time curve.
Adjust the Vd to see what happens to the t1/2 and the Cp-time curve.
minimum toxic concentration
minimum effective concentration