Dosagem e idade
Ajuste de dose com a idade
Because dose rate = Cpss x CL, the dose rate should be appropriate to the age of the patient.
Adjust age to see what happens to plasma concentration, as determined by clearance.
Then adjust the dose rate to keep the drug concentrations within the therapeutic window.
Cp mg/L
concentração tóxica mínima
concentração eficaz mínima
tempo