Pharmacodynamics
Índice terapêutico
The therapeutic index represents the relationship between concentrations causing adverse effects and concentrations causing desired effects.
It is usually EC50 (adverse effect)/EC50 (desired effect)
Drugs with a high or large therapeutic index are desirable in practice.
Move the slider to see how the curve changes.
Efeito (%)
Concentração (log)
Efeito desejado
Efeito adverso